- DHEA is a hormone secreted primarily by the adrenal glands. It results in a shift of a catabolic state to an anabolic or protein building state.
- It reduces cardiovascular risks by increasing lipolyses (decrease visceral fat).
- It stimulates the immune system, restores sexual vitality, improves moods, decreases cholesterol and body fat.
- It improves memory, increases energy, and has anti-cancer properties by enhancing the immune system.
- DHEA reduces insulin requirement
Adrenal hormone anabolic vs. catabolic metabolism
· Restores immunity
· Prevents osteoporosis, increases bone density
· Prevents cancer in lab animals
· Prevents diabetes & heart disease
· Decreases visceral fat
· Improves mood & well-being
· Improves energy & memory
· Slows aging process in lab animals
· Prevents lipid peroxidation = antioxidant
· Endocrine precursor to T.P.E.
· 7-keto DHEA is not a precursor to other HRT = avoid
· Neurotransmitter (recently discovered)
· Presently pending FDA approval for Lupus (Prasterone)
Clinically substantiated uses of DHEA include replacement for:
· Low DHEA levels
· Chronic disease
· Adrenal exhaustion or corticosteroid therapy
· Improving bone density
· Improving depression & mood disorders
· Enhancing immune response by activating T-cells
· Improving well-being
· Decreasing cardiovascular risk
· Improving erectile dysfunction
· Anyone over 40
· DHEA has never been shown to reverse the aging process
· Nevertheless DHEA is important for preventive medicine
· DHEA inhibits synthesis of thromboxane A2, reduces plasminogen
activator inhibitor, and tissue plasminogen activator – all decreasing
platelet aggregation and ischemia.
Men<200lb: 50mg AM
Men>200lb: 75-100mg AM
Women <50yo: 10-15mg AM
Women >50yo: 25mg AM
DHEA Serum Levels
MEN: Range 100-600
· Optimal 500-600
WOMEN: Range 50-300
· Optimal 200-250
· Over age 40 for health protection
· Preventive medicine and well-being
· Symptoms of aging, mood & depression